Dave Brancazio led the mechanical team that designed and built this high-throughput, fully automated DNA processing workstation.  The machine produced thousands of reactions per day for both PCR and cycle-sequencing applications. It integrated 96-channels of nanoliter pipetting, chilled micro-plate storage, manipulation of reagents and samples, barcode reading and data tracking, programmable thermal cycling and decontamination, and a four-axis robot with an automated tool-changer, all designed in-house. Work was supported by a $5M NIH grant. This machine was commercialized and marketed internationally under the name “Parallab 350”